25th Congress of the APSR
Plenary session
(scheduled as of 9 Nov 2021)Keynote / Presidential Lecture
- Keynote Lecture
The importance of the innate immuse response in resilience against COVID-19
Chair: Shu Hashimoto (Professor Emeritus, Nihon University, Japan)
Speaker: Stephen Townley Holgate (University of Southampton, UK) - Presidental Lecture
Our future; the path we’re on
Session summary: For the future to be healthy, we want to think about why COVID-19 is occurring and becoming more prevalent. Due to global warming, climate change, expansion of farmland and livestock grazing areas due to population growth, and infrastructure development, forests and wetlands, which are habitats for wild animals and birds, are decreasing or disappearing, and wild animals and birds are approaching livestock grazing areas and residential areas, increasing the opportunities for contact with livestock and people. As a result, zoonosis occurs; the COVID-19 outbreak and pandemic revealed the seriousness of the problem of disruption of natural ecosystems. Furthermore, the spread of infection has highlighted social inequities and disparities, i.e., social distortions. I will be giving a talk on this point and hope that you will have an opportunity to think about it.
Chairs: Akihito Yokoyama (Kochi Medical School, Kochi University, Japan)
Mari Hikichi (Nihon University School of medicine, Japan)
Speaker: Shu Hashimoto (Professor Emeritus, Nihon University, Japan)
Award Lecture
- Award Lecture 1: Michiyoshi Harasawa Memorial Award
A novel diagnostic and therapeutic strategy based on micro-aspiration
Chair: Shoji Kudoh (Japan Anti-Tuberculosis Association, Japan)
Speaker: Shinji Teramoto (Tokyo Medical University, Japan) - Award Lecture 2: Ann Janet Woolcock Memorial Award
Biomarker research in lung cancer
Chairs: Kim Young Whan (Konkuk University Medical Center, Republic of Korea)
Arth Nana (Mahidol University, Thailand)
Speaker: David CL Lam (University of Hong Kong, Hong Kong)
Expert View
- Japanese guideline for diagnosis and treatment of COVID-19
Chair: Kazuko Yamamoto (Nagasaki University Graduate School of Biomedical Sciences, Japan)
Speaker: Yasuyuki Kato (International University of Health and Welfare, Japan) - Overview of COVID-19
Session summary: The Overview of COVID-19 was outlined in the sections; i) pathogen and clinical features, ii) pathogenesis, iii) relationship between COVID-19 and idiopathic interstitial pneumonia (IIP), and iv) comparison between COVID-19 and influenza virus infection. The pathogen of COVID-19 is severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the receptor for this virus is angiotensin-converting enzyme 2 (ACE2). Since this ACE2 is distributed throughout the body, COVID-19 is an infectious disease that causes lesions throughout the body. In particular, COVID-19 greatly improved the understanding of the pathophysiology of respiratory viral infections. It has become clear that viral infections become more severe by inducing cytokines. COVID-19 also added a commentary on the pathological conditions that become more severe in the elderly and obese patients. Since the receptor for SARS-CoV-2 is expressed in type II alveolar epithelial cells, relationship between COVID-19 and IIP, those are mainly pathologically affected by type II alveolar epithelial cell injury, is of particular importance. It was revealed that radiological findings of COVID-19 are similar to those of IIP. Finally, we showed the difference from influenza, which is an important respiratory viral infection. Although both are RNA viruses, their clinical features are quite different because their receptors are different.
Chairs: Grace Sin-man Lam (Pamela Youde Nethersole Eastern Hospital, Hong Kong)
Junichi Kadota (Nagasaki City Hospital Organization Nagasaki Harbor Medical Center, Japan)
Speaker: Jiro Fujita (University of the Ryukyus, Japan) - Incorporation of Molecular Diagnostics for Severe Pneumonia
Chairs: Katsunori Yanagihara (Nagasaki University, Japan)
Tetsutaro Nagaoka (Juntendo University, Japan)
Speaker: Richard G Wunderink (Northwestern University Feinberg School of Medicine, USA) - Building a Walkable City and Infrastructure
Chairs: Celeste Mae L. Campomanes (St. Luke's Medical Center, Phillippines)
Shigeo Muro (Nara Medical University, Japan)
Speaker: Shinya Kuno (University of Tsukuba, Japan) - Host-Microbiome Interactions in the Pathogenesis of IPF
Session summary: Idiopathic pulmonary fibrosis (IPF) is a devastating pulmonary disease with no curative treatment other than lung transplantation. IPF results from maladaptive responses to environmental lung injury. I present published and unpublished evidence that the lung microbiome is an important contributor to the development of IPF. Specifically, I argue that innate immunity interacts with the microbiome during environmental lung injury, and dysregulation of this interaction (e.g., vie genetic polymorphisms) promotes dysbiosis, chronic inflammation and development/progression of IPF. I also provide unpublished data supporting that therapeutic activation of innate immunity may prevent and treat IPF. This presentation thus provides a cutting edge insight into novel pathogenesis and treatment pathways in IPF
Chairs: Yasunari Miyazaki (Tokyo Medical and Dental University, Japan)
Noboru Hattori (Hiroshima University, Japan)
Speaker: Stavros Garantziotis (National Institutes of Health, USA) - Advances in perioperative therapy: the new frontier
Session summary: Advances in target and immunotherapies have transformed the management of metastatic non-small cell lung cancer. More recently, the addition of immunotherapy has definitively prolonged the survival of stage III patients treated with chemoradiation therapy. The application of these therapies in the surgical management of early stage disease is an area of intense study, with some signals of efficacy. In this presentation, I will discuss the state of the data on neoadjuvant and adjuvant therapies for surgically resectable non-small cell lung cancer and ongoing trials, potential caveats and pitfalls, the potential for advancing biomarker research, and what the future may hold in this area.
Chairs: Sita Andarini (University of Indonesia - Persahabatan Hospital, Jakarta, Indonesia)
Kazuhisa Takahashi (Professor, Juntendo University, Graduate School of Medicine, Japan)
Speaker: David P. Carbone (The Ohio State University Comprehensive Cancer Center, USA) - A Role of the Pathologist in Personalized Medicine for Lung Cancer Patient
Chairs: Kazuyoshi Imaizumi (Fujita Health University, Japan)
Nobuaki Kobayashi (Yokohama City University Graduate School of Medicine, Japan)
Speaker: Mari Mino-Kenudson (Professor of Pathology, Harvard Medical School, MA, USA) - A New Paradigm for the Management of Mild Asthma
Chairs: Yuji Tohda (Kindai University Hospital, Japan)
Takeshi Kaneko (Yokohama City University, Japan)
Speaker: Paul O’Byrne (McMaster University, Canada) - Recent Advances in Severe asthma
Chairs: Kazuto Hirata (Osaka City University Hospital, Japan)
Naomi Tsurikisawa (Hiratsuka City Hospital, Japan)
Speaker: Nizar N. Jarjour (University of Wisconsin, Madison, WI. USA) - Approaches to lung endothelial cell repair in emphysema
Chairs: Hidenori Kage (The University of Tokyo, Japan)
Mitsuhiro Yamada (Tohoku University Hospital, Japan)
Speaker: Irina Petrache (National Jewish Health, USA) - Survival Skills for an Academic Career
Chairs: Jane Bourke (Monash University, Australia)
Sadatomo Tasaka (Hirosaki University Graduate School of Medicine, Japan)
Speaker: Lynn M Schnapp (School of Medicine and Public Health, University of Wisconsin-Madison, USA) - Career Development and Gender Equality to Achieve Sustainable Development
Chairs: Natasha E Smallwood (Alfred Hospital, Australia)
Toyohiro Hirai (Kyoto University, Japan)
Speaker: Tsuyako Nakamura (Doushisha University, Japan) - Racial and ethnic disparities in respiratory health
Chairs: Yasutaka Nakano (Shiga University of Medical Science, Japan)
Mayoko Tsuji (Tokyo Women's Medical University, Japan)
Speaker: Neeta Thakur (University of California, San Francisco, USA) - NHS pledges to go net zero carbon
Chairs: Agus Dwi Susanto (Universitas Indonesia-Persahabatan Hospital, Indonesia)
Satoshi Konno (Hokkaido University, Japan)
Speaker: Nick Watts (NHS, UK) - The public health implications of the Paris Agreement: a model study
Chairs: Paul Reynolds (Royal Adelede Hospital, Australia)
Yasuhiko Nishioka (The University of Tokushima, Japan)
Speaker: Ian Hamilton (The Lancet Countdown on Health and Climate Change, University College London, UK) - COVID-19 and its impact on the SDGs
Chairs: Mitsuko Kondo (Department of Respiratory Medicine, Tokyo Women's Medical University, Japan)
Shuichiro Maruoka (Nihon University School of Medicine, Japan)
Speaker: Mari Kosaka (Tokai University, Japan) - Deforestation and Zoonitic Disease
Chair: Yasuhiro Gon (Nihon University School of Medicine, Japan)
Speaker: Kimiko Okabe (Forestry and Forest Products Research Institute, Japan)
Special Programmes
- Special Programme 1
History, Present, and future of the APSR
Chairs: Michiaki Mishima (Saiseikai Noe Hospital/Professor Emeritus, Kyoto University, Japan)
Kwun M Fong (University of Queensland Thoracic Research Centre, The Prince Charles Hospital, Australia)
Yoshinori Hasegawa (National Hospital Organization Nagoya Medical Center, Japan)- The launch and early history of the APSR
Yoshinosuke Fukuchi (Juntendo University, Japan) - Present Status
Yoichi Nakanishi (Kitakyusyu City Hospital Organization, Japan) - Future
David CL Lam (University of Hong Kong, Hong Kong)
- The launch and early history of the APSR
- Special Programme 2
Message and lecture by representatives of sister society and president of 26th congress of APSR
Chairs: Toshihiro Nukiwa (Tohoku University, Japan)
Akihito Yokoyama (Kochi University, Japan)- Pulmonary embolism in patients with COVID-19
Marc Humbert (President of the ERS, South Paris University, France) - Sleep medicine in COVID-19 pandemic
Anita Simonds (Past President of European Respiratory Society, National Heart and Lung Institute, Imperial College London, UK) - COPD management in COVID-19 pandemic
Ki-Suck Jung (Hallym University College of Medical, Republic of Korea) - Restarting Respiratory Clinical Research in the era of the COVID-19 pandemic
Gregory P. Downey (President-elect of the ATS, University of Colorado Denver Anschtz Medical campus, USA)
- Pulmonary embolism in patients with COVID-19
