A selection of publications with educational value in
Respiratory Neurobiology and Sleep

Most recently added articles listed first

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  (Figure 2 of 10.1111/resp. 14526)
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  Ketogenic diet acutely improves gas exchange and sleep apnoea in obesity hypoventilation syndrome: A non-randomized crossover study
  Adam Osman, Chenjuan Gu, David E Kim, Daisy Duan, Bobbie Barron, Luu V Pham, Vsevolod Y Polotsky, Jonathan C Jun (DOI: 10.1111/resp.14526)
  onlinelibrary.wiley.com/doi/10.1111/resp.14526/full (August 2023)

  Comment by Dr Mark Lavercombe:
  This pilot study explores the use of a ketogenic diet in the management of patients with suspected obesity hypoventilation syndrome (OHS). Two weeks of high-fat, low-carbohydrate diet was associated with a reduction in PvCO2 of 3 mmHg; those with PvCO2 > 50 mmHg at baseline achieved a reduction in PvCO2 of 6.4 mmHg. The researchers intend further research using arterial blood gas sampling and a more robust diagnosis of OHS in order to further evaluate a possible role for a ketogenic diet in OHS management.

  20230706
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  (Figure 4 of 10.1111/resp. 14359)
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  Increased physical activity reduces sleep disturbances in asthma: A randomized controlled trial Natalia Febrini Passos, Patricia D Freitas, Regina Maria Carvalho-Pinto, Alberto Cukier, Celso R F Carvalho (DOI: 10.1111/resp.14359)
  onlinelibrary.wiley.com/doi/10.1111/resp.14359/full (January 2023)

  Comment by Dr Mark Lavercombe:
  In this randomised controlled trial of a forty-minute behavioural intervention once weekly for eight weeks in stable adult asthma patients, the authors report significant improvement in both asthma- and sleep-related outcomes. The intervention group achieved a substantial increase in their activity levels when compared with controls, with increases in daily step counts and the amount of moderate to vigorous physical activity per week, and reduction in sedentary time. Sleep efficiency and asthma control also improved. exposure to inhaled PM2.5 particles and lung adenocarcinoma is demonstrated, with increased levels of exposure associated with increased malignancy risk. Given the low rate of smoking in adult women in Taiwan (<5%), this data suggests another possible contributor to the development of adenocarcinoma in non-smoking women.

  20221208
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  Periodic limb movements during sleep and blood pressure changes in sleep apnoea: Data from the European Sleep Apnoea Database Carolina Lombardi; Gianfranco Parati; Davide Soranna; Antonella Zambon; Paweł Sliwinski; Gabriel Roisman; Jean-Louis Pepin; Sophia Schiza; Renata Riha; Pavol Joppa; Ingo Fietze; Jan Hedner; Ludger Grote; the European Sleep Apnoea Database (ESADA) Collaborators (DOI: 10.1111/resp.13760)
  onlinelibrary.wiley.com/doi/10.1111/resp.13760/full (Aug 2020)

  Comment by Dr Mark Lavercombe:
  The association between obstructive sleep apnoea and cardiovascular disease is well recognised. In this paper, the authors explore the role of comorbid elevation of the periodic limb movements in sleep index in a cohort of of patients with obstructive sleep apnoea, and demonstrate a significant elevation in systolic blood pressure, even after accounting for the degree of OSA with multivariate analysis. Further studies - including those utilising 24h BP monitoring - are recommended.

  20200721
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  Year in review 2017: Interstitial lung disease, pulmonary vascular disease and sleep Amanda J Piper, Stephen J Wort, Elisabetta A Renzoni, Vasileios Kouranos (DOI: 10.1111/resp.13273)
  onlinelibrary.wiley.com/doi/10.1111/resp.13273/full (Feb 2018)
  20180313
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  Airway stenting in the management of iatrogenic tracheal injuries: 10-Year experience Tazi-Mezalek et al. DOI: 10.1111/resp.12853
  onlinelibrary.wiley.com/doi/10.1111/resp.12853/full (Jul 2016)

  Comment by Dr Mark Lavercombe:
  This paper describes the experience of managing a very rare complication of endotracheal intubation or tracheostomy, including the nature and anatomical distribution of the injuries. Finally, outcomes using different treatment approaches is discussed.

  20161021

• Usefulness of transcutaneous PCO₂ to assess nocturnal hypoventilation in restrictive lung disorders. Georges et al.
  onlinelibrary.wiley.com/doi/10.1111/resp.12812/full (May 2016)
  (Editorial: onlinelibrary.wiley.com/doi/10.1111/resp.12871/abstract)

  20160915

• Association of sleep apnoea with chronic kidney disease in a large cohort from Taiwan. Chu et al.
  onlinelibrary.wiley.com/doi/10.1111/resp.12739/abstract (Jan 2016)
  (FREE access: Editor's Choice; Editorial: onlinelibrary.wiley.com/doi/10.1111/resp.12796/abstract)

  20160819

• Impact of effective versus sham continuous positive airway pressure on liver injury in obstructive sleep apnoea: Data from randomized trials. Jullian-Desayes et al.
  onlinelibrary.wiley.com/doi/10.1111/resp.12672/abstract (Nov 2015)
  (Editorial: onlinelibrary.wiley.com/doi/10.1111/resp.12720/abstract)

  20160819