Respirology Case Reorts

Avinash A Nair, Prince James, Leena Robinson Vimala, Thomas Kodiatte, Richa Gupta
DOI: 10.1002/rcr2.1411

This study presents the largest case series of Bronchial Dieulafoy's disease (BDD), a rare vascular disorder causing massive haemoptysis Seven cases from a single centre were retrospectively analysed, including up to 4-year follow-up outcomes The study underscores the need for bronchoscopy surveillance, imaging and emphasizes embolization and endobronchial therapy for management

Masamitsu Hamakawa, Ayaka Tanaka, Fumiaki Tokioka, Tadashi Ishida
DOI: 10.1002/rcr2.1412

Several reports have described dupilumab-induced eosinophilic pneumonia (EP) after treatment with dupilumab in patients with type 2 inflammatory disease Other reports have suggested the efficacy of dupilumab for chronic EP (CEP) Whether dupilumab can be continued in patients with type 2 inflammatory disease who develop EP during dupilumab treatment remains unclear We present herein three cases with different clinical presentations involving dupilumab and EP

XiaYi Miao, Wei Yang, Shiqiang Wang, Jihong Tang, XuMing Luo, Teng Chen
DOI: 10.1002/rcr2.1391

Tannerella forsythia can lead to pneumonia and abscesses under special conditions, including co-infection with helper pathogens and reduced host immunity mNGS represents an effective method for diagnosis of the causative pathogen in lung abscess The course of its treatment should last for at least 3 months

Ayşe Şahin Tutak
DOI: 10.1002/rcr2.1394

Extremely high D-dimer levels are closely related to oxygen saturation/prognosis and may be accompanied by ATIII deficiency ACT levels may prove to be a guide when ATIII levels cannot be measured When ATIII supplementation is required, an adequate response may be achieved by FFP 10-20 mL/kg/day while maintaining a high level of anticoagulant support in the treatment protocol

Zixuan Liu, Xiaoli Deng, Yanhong Du, Danxiong Sun
DOI: 10.1002/rcr2.1402

We report a case of a 33-year-old woman with recurrent hemoptysis for 1 year The patient did not exhibit a temporal relationship between her periods and the onset of hemoptysis A chest computed tomography scan showed multiple pseudocavities in the lower lobe of the right lung and multiple nodules in both lower lobes of the lungs The right lower lobe wedge resection was performed Postoperative pathological examination showed pulmonary endometriosis which is a rare cause of hemoptysis

Naoko Arakawa, Yuno Shiota, Fumi Onizawa, Fumi Miyata, Azusa Miyoshi, Tomohiro Akaba, Mayoko Tsuji, Ken Arimura, Osamitsu Yagi, Mitsuko Kondo, Hideki Katsura, Etsuko Tagaya
DOI: 10.1002/rcr2.1403

Here, we describe a case of autoimmune PAP (APAP) treated with corticosteroids and immunosuppressive agents for nonspecific interstitial pneumonia (NSIP) associated with clinically amyopathic dermatomyositis (CADM) APAP manifested during immunosuppressive therapy for IP associated with CADM, and it was speculated that NSIP associated with CADM and subclinical APAP coexisted at the time of NSIP diagnosis

Yuto Kato, Kentaro Fukunaga, Aya Ooka, Shunichi Tokuoka, Yoko Kataoka, Takuya Fujita, Hiroyuki Sugihara, Masafumi Yamaguchi
DOI: 10.1002/rcr2.1404

We report a unique case of transudative pleural effusion associated with IgG4-related disease in an 80-year-old man with multiple comorbidities Despite initial treatment with diuretics, the effusion persisted, prompting further investigation Medical thoracoscopy revealed lymphatic follicle hyperplasia and an abundance of IgG4-positive plasmacytoid cells, confirming IgG4-related pleuritis

Tomoya Baba, Takayasu Ito, Yoshiki Sato, Shunsaku Hayai, Junji Koyama, Shota Nakamura, Yoshiyuki Tokuda, Toyofumi Fengshi Chen-Yoshikawa, Makoto Ishii
DOI: 10.1002/rcr2.1405

We present a case of massive haemoptysis in which bleeding was controlled by bronchial occlusion with endobronchial Watanabe spigots (EWSs) using a two-scope technique while securing the field of view

Anthony Carrozzi, Rex Chu, William Nigole, Hariette Goldman, Serena Hope, Richard Li, Con Archis
DOI: 10.1002/rcr2.1406

We describe the case of an 87-year-old gentleman referred to a metropolitan hospital in Sydney with pneumomediastinum complicating immunotherapy associated pneumonitis and recent bronchoscopic intervention The contribution of pneumonitis in the setting of interstitial lung disease has been well described to developing pneumomediastinum however this is less clear in the setting of immunotherapy associated pneumonitis and to what extent bronchoscopic intervention compounds this risk

Naoki Fujimoto, Kohei Fujita, Ayami Ishida, Koki Moriyoshi, Kiminobu Tanizawa
DOI: 10.1002/rcr2.1407

Pathological images of the left lower lobe showing thyroid transcription factor (TTF)-1 negativity (C) and mucin (MUC)5 AC positivity (D) on immunostaining and no bilayer on p63 staining (E), consistent with the features of ciliated adenocarcinoma

Harriet J Caterson, Sewon Kim, Matthew Zaborowski, Michael Harden, Michael Hibbert
DOI: 10.1002/rcr2.1408

An unusual case of persistent consolidation in a gentleman requiring significant invasive and radiological investigation resulting in a rare diagnosis of an interstitial lung disease Optimal management strategies are unclear and this case highlights the potential of close monitoring rather than immunosuppression for these patients

Khai Lip Ng, Nai-Chien Huan, Wei Loon Tan, Nur Husna Mohd Aminudin, Fazilah Hassan, Kasuma Mohamed Nordin
DOI: 10.1002/rcr2.1409

We present a 73-year-old gentleman with a rare dual pathology of endobronchial aspergilloma and endobronchial adenocarcinoma who initially presented with prolonged cough, dyspnoea, and haemoptysis Bronchoscopy revealed an obstructed bronchus by a necrotic mass whereby histological examination showed evidence of Aspergillus spp infection which persisted despite treatment with anti-fungal agents Repeated bronchoscopy and biopsy eventually unravelled an underlying endobronchial adenocarcinoma

Cheuk Cheung Derek Leung, Hiu Ching Christy Chan, Ming Chiu Chan, Yu Hong Chan, Man Ying Ho, Chun Hoi Chen, Ching Man Ngai, Yiu Cheong Yeung
DOI: 10.1002/rcr2.1414

A 24-year-old man developed fever and painful neck swelling 1 month after recovering from COVID-19 He was diagnosed with post COVID-19 Kikuchi-Fujimoto disease

Takako Kawaguchi, Kei Yamasaki, Saki Shigemi, Hiroki Dosaka, Riho Hirosawa, Taiga Nagasawa, Satoshi Fujimoto, Shohei Shimajiri, Kazuhiro Yatera
DOI: 10.1002/rcr2.1416

We report a case of combined small cell lung carcinoma (c-SCLC) with adenocarcinoma and chondrosarcoma-like features and mediastinal lymph node metastasis of only SCLC components The diagnosis was complex and finally achieved due to a left upper lobectomy

Hanson Siu, Ari Mond, James Shaw, Ruth Chin, Patrick Hosking, Hari Wimaleswaran
DOI: 10.1002/rcr2.1418

Amyloidosis is a pathological deposition disease that causes a spectrum of organ dysfunction Lung involvement of transthyretin (ATTR) amyloid is thought to be a senile disease observed usually as a finding at autopsy We describe the first case of pulmonary ATTR amyloidosis from Australia with concurrent mycobacterial tuberculosis infection

Yuka Izumiya, Hidesato Odaka, Toru Kikuchi, Yuri Takita, Takuo Tokairin
DOI: 10.1002/rcr2.1419

Granulocyte colony-stimulating factor (G-CSF)-producing lung tumours are rare, with their imaging features and effective treatments remaining elusive Similarly, mesenchymal-epithelial transition (MET) exon 14 skipping mutations are also uncommon Herein, we report a case of G-CSF-producing lung adenocarcinoma positive for a MET exon 14 skipping mutation, mimicking lung abscess

Bapti Roy, Bianca M Iacopetta, Carolyn J Peddle-McInytre, Michaela Donaghy, Matthew Ing, Ai Ling Tan, Y C Gary Lee
DOI: 10.1002/rcr2.1410

This is the protocol for the PLEASE-3 study The PLEASE-3 study will evaluate bendopnoea as a screening test for effusion-related breathlessness, its predictive value of symptomatic benefits from fluid drainage and explore its underlying physiological mechanism This is the first study to investigate bendopnoea in patients with pleural effusion

Sakditad Saowapa, Nattanicha Chaisrimaneepan, Natchaya Polpichai, Pharit Siladech, Lukman Tijani
DOI: 10.1002/rcr2.1397

A 44-year-old female with Stage IIA mucinous adenocarcinoma developed a hydropneumothorax after right middle and lower lobe resection due to an air leak from the surgical stump Managed with an Amplatzer plug and chest tube drainage, her condition improved significantly This case highlights the importance of careful management in preventing serious outcomes from such complications

Ghazal Roostaei, Alireza Asgari, Hossein Kazemizadeh, Hamidreza Abtahi, Maryam S Fakhri B, Niloofar Khoshnam Rad
DOI: 10.1002/rcr2.1398

This case highlights the value of EBUS-TBNA in diagnosing metastatic melanoma, particularly when the macroscopic appearance of the aspirate, with visualization of black pigments, suggests the diagnosis

Yuriko Sueda, Hirokazu Tokuyasu, Hiromitsu Sakai, Akira Yamasaki
DOI: 10.1002/rcr2.1399

We report a rare case of pulmonary Mycobacterium shinjukuense infection with cavitary lesion Chemotherapy with rifampicin, ethambutol, and clarithromycin was effective for the lesion

Hiroshi Ohnishi, Taro Horino, Hideki Nakajima, Akihito Yokoyama
DOI: 10.1002/rcr2.1415

Pulmonary cryptococcosis presents as a solitary nodule or as multiple pulmonary nodules We present a case of pulmonary cryptococcosis mimicking lung cancer with multiple lung metastases